Paroxetine hydrochloride

Side effects that you should report to your doctor or health care professional as soon as possible:

allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
black or bloody stools, blood in the urine or vomit
fast, irregular heartbeat
hallucination, loss of contact with reality
painful or prolonged erection (men)
seizures
suicidal thoughts or other mood changes
trouble passing urine or change in the amount of urine
unusual bleeding or bruising
unusually weak or tired
vomiting

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

change in appetite, weight
change in sex drive or performance
constipation or diarrhea
difficulty sleeping
drowsy
headache
increased sweating
muscle pain or weakness
tremors

This list may not describe all possible side effects.

Visit your doctor or health care professional for regular checks on your progress. Continue to take your medicine even if you do not immediately feel better. It can take several weeks before you feel the full effect of this medicine.

Patients and their families should watch out for depression or thoughts of suicide that get worse. Also watch out for sudden or severe changes in feelings such as feeling anxious, agitated, panicky, irritable, hostile, aggressive, impulsive, severely restless, overly excited and hyperactive, or not being able to sleep. If this happens, especially at the beginning of antidepressant treatment or after a change in dose, call your health care professional.

If you have been taking this medicine regularly for some time, do not suddenly stop taking it. You must gradually reduce the dose or your symptoms may get worse. Ask your doctor or health care professional for advice.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol can increase or decrease the effects of this medicine. Avoid alcoholic drinks.

Store your medicines at room temperature between 68-77 degrees F (20-25 degrees C) away from light and moisture. Do not store your drugs in the bathroom. Keep all drugs away from reach of children and pets. Throw away any unused medicine after the expiration date.

PAROXETINE is used to treat depression. It may also be used to treat anxiety disorders, obsessive compulsive disorder, panic attacks, post traumatic stress, and premenstrual dysphoric disorder (PMDD).

They need to know if you have any of these conditions:

bipolar disorder or a family history of bipolar disorder
heart disease
kidney or liver disease
receiving electroconvulsive therapy
seizures (convulsions)
suicidal thoughts or a previous suicide attempt
an unusual or allergic reaction to paroxetine, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding

Take this medicine by mouth with a glass of water. You can take it with or without food. Take your medicine at regular intervals. Do not take your medicine more often than directed. Do not stop taking except on your doctor's advice. Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

NOTE: This medicine is only for you. Do not share this medicine with others.

If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Do not take this medicine with any of the following:

certain diet drugs like dexfenfluramine, fenfluramine, phentermine
MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
medicines similar to paroxetine like fluoxetine, sertraline, citalopram
phenothiazines like thioridazine
pimozide
procarbazine
St. John's wort
tryptophan

This medicine may also interact with the following:

aspirin and aspirin-like drugs
cimetidine
digoxin
fosamprenavir
linezolid
medicines for depression, anxiety, or psychotic disturbances
medicines for migraine headache like almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, sumatriptan, zolmitriptan
medicines that treat or prevent blood clots like warfarin, enoxaparin, and dalteparin
NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen
phenobarbital
phenytoin
procyclidine
ritonavir
theophylline

This list may not describe all possible interactions. Give your health care providers a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

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Paxil (paroxetine) prescribing information
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